Policies and Procedures

Institutional Policy on the Use of Animals in Research and Teaching Activities

Individual IACUC Policies:

Drugs, Euthanasia, and Compound Administration

• • Recommended Doses of Anesthetics and Analgesics of Laboratory Animals
  • Hypodermic and Gavage Needle Use and Injection Policy
  • Policy on the Use of Non-Pharmaceutical-Grade Compounds and Expired Materials-2022
  • Ether Use Policy
  • Policy on Euthanasia and Secondary Methods of Euthanasia in Animals

Restraint and Surgery

• • Physical Restraint
  • Tips Only Rodent Surgery
  • Standard Rodent Surgery
  • Aseptic Surgery for USDA Covered Species
  • Multiple Major Survival Surgery
  • Transcardial Perfusion Surgical Addendum (to be added to animal protocol)
  • Guidelines for the Acclimation for Conscious Restraint of Rats and Mice for fMRI

Technical Procedure Policies

• • The Prevention, Recognition, and Treatment of Pain & Distress in Laboratory Animals
  • Tumor Implantation, Use, and Clinical Endpoints
  • Required Stabilization Before Animal Use
  • Tissue and Fluid Use Policy
  • Policy on Identification Methods and Genotyping Laboratory Rodents
  • Blood Collection from Common Laboratory Animals
  • Polyclonal Antibody Production
  • Custom Antibody Production
  • Ascites Production
  • Protocol Requirements for the Use of Live Embryonated Eggs(contact IACUC Office for Policy)
    
  • Policy on Frog Oocyte Harvesting
  • Retro Orbital Injections in Mice

Animal Transportation, Diet, and Supervision

• • Transportation of Laboratory Animals
  • IACUC Approval Letters for Grants
  • Animal Cage Identification and Specialized Cage Identification Cards
  • Importation and Exportation of Animals to and from Atypical Sources
  • Policy on Food/Water Restriction or Deprivation
  • Reporting Deficiencies in Animal Care and Use
  • Northeastern University Post Approval Quality Assurance Program-PAQA
  • Policy on Genetically Engineered Animals, the Use of Recominant Materials, & The Institutional Biosafety Committee (IBC)
  • Single Housing of Laboratory Animals
  • Enrichment of Laboratory Animals

Protocol Review

• • Policy on IACUC Review Procedures
  • Policy on Review of Amendments to Approved Protocols
  • Amendment Policy Supplement: IACUC Approved Guidance Documents for VVC
  • Policy on Requiring a Congruency Comparison Prior to Release of IACUC Approval Dates for Northeastern University
  • Pain and Distress Categorization for Animal Protocols and Amendments
  • Continuing Review of Protocols Using Animals in Research
  • Policy on Prompt Reporting of Noncompliance and Adverse Events (AE)

Researcher Training Requirements

• • Medical Surveillance Program for Persons Working with Research Animals in the Laboratory, Classroom, and Field Studies